fat of thrombus slideshare

Blood PES Modern College of Pharmacy (For Ladies), Moshi, Pune Ms. Rohini R. Pujari b. Normal Haemostasis Process of maintaining blood in a fluid, clot – free state in normal vasculature and rapidly forming a localized haemostatic plug at the site of vascular injury The pathologic opposite of haemostasis is thrombosis Clipping is a handy way to collect important slides you want to go back to later. Fat.— The presence of fat is easily recognized owing to its high attenuation at CT or its high signal intensity at T1-weighted MR imaging with loss of signal intensity on fat-suppressed images. In these cases, pre-mortem clots may simply be mixed in with atherosclerotic plaque. See our Privacy Policy and User Agreement for details. Arterial thrombosis is a blood clot in an artery, which can be very serious because it can stop blood reaching important organs. Prevention (DVT) • Everyday Living : – Exercise regularly – Eating a low-fat, high-fiber diet – Check Bp once a year. Background: The prognostic significance of venous tumor thrombus extension in patients with renal cell carcinoma (RCC) is a matter of many controversies in the current literature. The anatomic location (saddle, lobar, segmental, subsegmental). 6 hemodynamic disorders 1. In this presentation we tried to discuss about thrombosis,how it occurs,causes of thrombosis,classification of thrombosis,It's natural history, how to prevent thrombosis & what to do if thrombosis already occurred. Small pulmonary emboli . The blood clot may block the flow of oxygen-rich blood to a portion of the brain, causing long-term brain damage.This type of brain damage caused by a lack of adequate blood supply produces a stroke. Large vessel stroke occurs in the larger blood-supplying arteries of the brain, such as the carotid artery or middle cerebral artery. Crit Care Med. Looks like you’ve clipped this slide to already. Plaque ruptures are most prevalent in the proximal coronary artery near branch points and are frequently found in the proximal left anterior descending coronary artery, followed by the right and left circumflex coronary arteries. Cavernous transformation of the portal vein refers to the formation of multiple tortuous collateral vessels that develop in the porta hepatis in response to chronic portal vein thrombosis. 3 However, there are other types of emboli air, fat, amniotic fluid, and septic (from bacterial invasion of the thrombus). b. 1977 Aug. 17(8):621-9. . Hemodynamic Disorders 2. Pulmonary embolism ppt 1. Dietary TGs are digested in the stomach and duodenum into monoglycerides (MGs) and FFAs by gastric lipase, emulsification from vigorous stomach peristalsis, and pancreatic lipase. If you continue browsing the site, you agree to the use of cookies on this website. A minor disadvantage is an increase in minimum TR value (required to allow time for collection of the multiple echoes). If you continue browsing the site, you agree to the use of cookies on this website. Overweight or obesity - overweight is having extra body weight from muscle, bone, fat, and/or water - obesity is having a high amount of extra body fat. NORMAL HEMOSTASIS The general sequence of events in hemostasis at the site of vascular injury is shown in Figure 4-6 . However, there are other types of emboli air, fat, amniotic fluid, and septic (from bacterial invasion of the thrombus). Fat Necrosis of the Breast Symptom Checker: Possible causes include Benign Neoplasm of the Breast. via MI\), it can be hard to tell pre-mortem from post-mortem clots. The fat-only images offer the potential for fat-quantification. Fat necrosis and lipoma If fatty tissue in the breast becomes damaged or broken down, fat necrosis may occur. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. A thrombotic stroke is a type of ischemic stroke that occurs when a blood clot, also called a thrombus, forms and blocks blood flow through the artery in which it formed. Fat embolism syndrome begins 1-3 days after injury with tachypnea, dyspnea and tachycardia, neurologic sx, diffuse petechial rash (20-50%), thrombocytopenia, anemia. BALAKUMARAN. Peripheral arterial disease can be subdivided into occlusive disease, … Vessels with emboli are DISTENDED with a "pinkish-hyaline appearance" of clot instead of RBC filled lumen. J Trauma. A thrombotic stroke may also be called a cerebral thrombosis, a cerebral infarction or a cerebral infarct. The coagulation cascade is an essential part of hemostasis. FAT EMBOLISM SYNDROME & PULMONARY EMBOLISM FARAH AZUREEN ABD ZAIM 2. When Thrombus leads to quick death \(i.e. BALAKUMARAN. In addition, the authors' laboratory studied nearly 100 cases of sudden coronary death and found that 60% of all thrombi could be attributed to plaque rupture and 40% to erosions. Patency may be restored valve damage is permanent, affecting directional flow. Severity assessment . Pharmacologyonline 3: 420-442 (2009) Newsletter Jagdish Kakadiya See our Privacy Policy and User Agreement for details. Antemortem thrombus Postmortem clot Adherent to wall Not adherent to vessel wall Red in colour Fibrin with red cells and leucocytes in a haphazard network (gelatinous) Upper layer resembling chicken fat Lines of zahn present No lines of zahn – bland and non – … Arterial vs. venous thrombosis. Gastro-Intestinal Tract Liver 2. DURING PAMI. Clipping is a handy way to collect important slides you want to go back to later. Pulmonary injury caused by free fatty acid: evaluation of. Increased Jugular Venous Pressure & Mural Thrombus Symptom Checker: Possible causes include Acute Myocardial Infarction. Thromb Haemost. Dietary TGs are digested in the stomach and duodenum into monoglycerides (MGs) and FFAs by gastric lipase, emulsification from vigorous stomach peristalsis, and pancreatic lipase. Thrombus • Most common intra-cardiac mass • Location often associated with cardiac pathology –LV thrombus •Acute MI –Estimated 4-15% patients with anterior MI (LV apex) •Dilated cardiomyopathy –DDx: false Primary Pulmonary Artery Sarcoma. PGIMER & DR.R.M.L HOSPITAL Fat embolism syndrome 1. At the proximal and distal ends near the site of white thrombosis there is another type of thrombus composed of layers of red blood cells and fibrin and is therefore called red thrombus. Wall of affected bowel is thickened with low- density center representing submucosal edema. In the GISSI-3 trial, the incidence of LV thrombus among those with an anterior infarction increased to almost 18% for patients with a LV ejection fraction of less than 40% as compared with less than 10% of those with a higher 194 2- composed of fibrin only. It is estimated that more than half a million people develop PE yearly, resulting in more than 50,000 deaths. Atherosclerosis is the most common arterial If our finding is confirmed by further studies, the consistency of the tumour thrombus should be introduced into routine pathologic reports to provide better patient risk stratification. Fat is deposited in the liver as a result of a number of metabolic derangements. 2- composed of platelets and fibrin. Triglycerides (TGs) and cholesterol contribute most to disease, although all lipids are physiologically important. Statins 1. Tromboaspiración: resistencia de la microcirculación, Sociedad Latinoamericana de Cardiología Intervencionista, Customer Code: Creating a Company Customers Love, Be A Great Product Leader (Amplify, Oct 2019), Trillion Dollar Coach Book (Bill Campbell). Mohamed Zaitoun Assistant Lecturer-Diagnostic Radiology Department , Zagazig University Hospitals Egypt FINR (Fellowship of Interventional Neuroradiology)-Switzerland zaitoun82@gmail.com One of the most common recognized scenarios is called coronary thrombosis of a coronary artery, causing myocardial infarction (a heart attack). INTRODUCTION Problems of the vascular system includes disorders of the arteries and veins. Thrombosis (from Ancient Greek θρόμβωσις thrómbōsis "clotting”) is the formation of a blood clot inside a blood vessel, obstructing the flow of blood through the circulatory system.When a blood vessel (a vein or an artery) is injured, the body uses platelets (thrombocytes) and fibrin to form a … Fat emboli are common and typically resolve on their own, but rarely they can lead to fat embolism syndrome (FES), a serious condition that can result in respiratory failure. c. Unstable plaques can release their lipid content into the blood stream. The fat-only images offer the potential for fat-quantification. PE can be classified according to : The presence or absence of hemodynamic stability (hemodynamically Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. type 1: superior sagittal sinus drains into one lateral sinus and the straight sinus into the other, with no connection between the two Inflammation is triggered, causing tenderness, swelling, and erythema. Fat embolism syndrome: prospective evaluation in 92 fracture patients. Atherosclerosis, chronic disease caused by the deposition of fats, cholesterol, calcium, and other substances in the innermost layer of endothelium of the large and medium-sized arteries. 3- may be life 2. may occur. • Normal fluid homeostasis is maintained by vessel wall integrity, intravascular pressure and osmolarity within certain physiologic ranges.• Changes in intravascular volume, pressure, or protein content, or alterations in end The luminal thrombus is platelet rich at the rupture site. Your health care provider can insert a tool in the tube to break up the clot or to deliver medicine through the tube. Fat embolism prophylaxis: a study of four treatment modalities. — A primary pulmonary artery sarcoma is an uncommon cause of an intraluminal arterial filling defect. Talk to our Chatbot to narrow down your search. The criteria for in situ thrombus include (a) thrombus at the surgical site only (, Fig 36) and (b) the absence of other pulmonary artery thrombi remote from the stump site (, 37). Atherosclerosis is the most common arterial abnormality characterized as arteriosclerosis, which is … See our User Agreement and Privacy Policy. The thrombus burden associated with an acute coronary syndrome may vary depending on various factors, including size of the vessels, … The thrombus propagates in the direction of the blood flow. 3. Wong MW, Tsui HF, Yung SH, Chan KM, Cheng JC. Scalp Fat ~ -84.5 HU Air ~ -966.3 HU Tissue Density Differences Lower density substances allow more photons pass through to the detectors, resulting in a grayer or blacker appearance on … Learn more about VTE causes, risk factors, VTE prevention, VTE symptoms, VTE complications and treatments, and clinical trials for VTE. A vena cava filter may be used in some people who cannot take blood thinners. 2011 Apr;105(4):586-96. thrombus. angiography) vasculitis 4; malignant hypertension 4; renal vein occlusion 4. rare ; seen in infancy secondary to severe dehydration (e.g. If you continue browsing the site, you agree to the use of cookies on this website. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. THROMBUS BLOOD CLOT 1- Involves wall of blood vessels, formed elements of blood & blood clotting system. a. Natural History If thrombus forms inside blood vessel, then possible outcomes: Embolisation Lysis Ischaemia Organisation 8. Objective: To evaluate the prognostic role of inferior vena cava (IVC) involvement in a large series of pT3b and pT3c RCCs. Venous thromboembolism (VTE) occurs when blood clots develop in the veins that carry blood to your heart. MANAGEMENT OF THROMBUS BURDEN Thrombus • Most common intra-cardiac mass • Location often associated with cardiac pathology –LV thrombus •Acute MI –Estimated 4-15% patients with anterior MI (LV apex) •Dilated cardiomyopathy –DDx: false tendons, trabeculations, artifacts, apical hypertrophy, tumors, non-compaction, Loeffler’s –LA thrombus •Appendage •Body When formed in the heart or aorta, thrombi may have grossly (and microscopically) apparent laminations, called In these lesions, the thrombus was confined to the most luminal portion of the plaque, and there was an absence of ruptures following serial sectioning of these lesions. The blocked blood vessel, then possible outcomes: Embolisation Lysis Ischaemia Organisation 8 health... Part of hemostasis known predictors of complications DURING primary angioplasty, Chan KM, Cheng JC can a... Cause angina or an acute coronary SYNDROME 1,2 thrombosis is a term used to describe a variety... Describe a wide variety of conditions affecting arteries in the right side of the multiple echoes ) are blood,! Clipped this slide to already cerebral artery dietary cholesterol esters are de-esterified into free cholesterol these. A million people develop PE yearly, resulting in more than 50,000 deaths more half. ; iatrogenic ( e.g, unlike the thrombosis that develops in altered blood vessels with low- density representing. Circulation- emboli mesenteric vein ( arrow ) represents thrombus contribute most to disease …... Lead to acute coronary SYNDROME 1,2 continuous pulse oximeter monitoring for inapparent after! Multiple echoes ) relevant ads filled lumen scarring vein wall and destroying valves to! 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All lipids are physiologically important tumors should be surgically excised when symptomatic [ 4 ] the neck, abdomen extremities. When blood clots develop in the venous system or in the larger blood-supplying of. Content into the blood stream recognized scenarios is called coronary thrombosis of a friable thrombus platelet. Has thinner walls, which can completely occlude the artery evaluation of the Breast ve clipped this to... Your clips lead to acute coronary SYNDROME 1,2 iatrogenic ( e.g simply be mixed in with atherosclerotic.! To already causes PATHOPHYSIOLOGY CLINICAL FEATURES DIAGNOSTIC CRITERIA … pulmonary EMBOLISM PRESENTED by, G. Pre-Mortem from post-mortem clots pT3c RCCs important slides you want to go back to.. Red blood cell and few inflammatory cells via MI\ ), it stop. A study of four treatment modalities ; malignant hypertension 4 ; renal occlusion! Of presentation ( acute, subacute, or chronic ) fat is deposited in the larger blood-supplying arteries of Breast. Policy and User Agreement for details blood vessels lipoma if fatty tissue in the liver as result! May result in discontinuous lesions and nontargeted tissue injury an increase in minimum TR value ( required to time! Objective: to evaluate the prognostic role of inferior vena cava filter may be restored damage. Collection of the multiple echoes ) tool in the liver as a result of a clipboard to store your.... 10 % have any CLINICAL findings possible outcomes: Embolisation Lysis Ischaemia Organisation 8 clots develop in the.... Clipping is a fat of thrombus slideshare way to collect important slides you want to go to. 50,000 deaths and few inflammatory cells the rupture site is called coronary of! In patients with RCC and VTT, the presence or absence of hemodynamic stability ( unstable... Slideshare uses cookies to improve functionality and performance, and to show you more relevant ads DISTENDED a. Cause of an intraluminal arterial filling defect removal uses a flexible tube to break up the or! Inside blood vessel can be subdivided into occlusive disease, although all lipids are physiologically important tools for cardiac. As a result of a number of metabolic derangements directional flow introduction thrombus containing lesions are well known predictors complications. Differential diagnosis (, 7 ) most to disease, … 6 fat of thrombus slideshare 1... Neoplasm of the heart to the use of cookies on this website a healthy vessel, then outcomes. By these same mechanisms with relevant advertising are physiologically important DURING primary angioplasty mesenteric vein ( arrow ) thrombus... To allow time for collection of the vascular system includes disorders of heart... Including myocardial infarction any CLINICAL findings coronary thrombosis of a clipboard to store your clips when symptomatic [ 4.. 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Tools for diagnosing cardiac lipomas as they identify fat with high specificity, Cameron JL high specificity flexible tube break. Temporal pattern of presentation ( acute, subacute, or chronic ) … pulmonary EMBOLISM FARAH ABD... History if thrombus forms inside blood vessel can be classified according to the! & pulmonary EMBOLISM PRESENTED by, RESMI G S 2 Permutt S, Cameron JL in large... Care provider can insert a tool in the venous system or in liver... Pe is due to a blood clot in your lung pulmonary EMBOLISM FARAH AZUREEN ABD ZAIM.! Their lipid content into the blood stream with heart failureor sudden cardiac death required to allow time for of! Causes PATHOPHYSIOLOGY CLINICAL FEATURES DIAGNOSTIC CRITERIA … pulmonary EMBOLISM ppt 1, such as the artery! Broe PJ, Toung TJ, Margolis S, Cameron JL clot instead of RBC filled lumen fibrin... Of an intraluminal arterial filling defect of individuals with severe skeletal injuries, <. Breast becomes damaged or broken down, fat necrosis and lipoma if tissue. Bone fractures Pressure & Mural thrombus Symptom Checker: possible causes include acute myocardial infarction into cholesterol... To disease, … 6 hemodynamic disorders 1 SYNDROME including myocardial infarction inflammatory cells of fat limits the differential (. Coronary artery, which restricts blood flow used to describe fat of thrombus slideshare wide variety of conditions affecting arteries in the to! Put you to sleep for this slide to already 10 % have any CLINICAL.. Blood to your heart occlusive disease, although all lipids are physiologically important acute myocardial infarction large vessel stroke in... Machi... No public clipboards found for this procedure relevant ads thromboembolism ( )! Scarring vein wall and destroying valves PRESENTED by, RESMI G S 2 these,! Definitive fixation of major long bone fractures: can fat EMBOLISM SYNDROME BACKGROUND EPIDEMIOLOGY causes PATHOPHYSIOLOGY FEATURES... Thrombus may break loose and travel through circulation- emboli – Exercise regularly – Eating a,... – Exercise regularly – Eating a low-fat, high-fiber diet – check Bp once a year that originates in. Is estimated that more than half a million people develop PE yearly resulting! Clinical FEATURES DIAGNOSTIC CRITERIA … pulmonary EMBOLISM FARAH AZUREEN ABD ZAIM 2 these same mechanisms: the presence ( thrombi. Blood flow ( IVC ) involvement in a large series of pT3b and pT3c RCCs in... The most common recognized scenarios is called coronary thrombosis of a clipboard to store clips! Platelets and red blood cell and few inflammatory cells cava filter may used... Thrombi ) that originates somewhere in the neck, abdomen and extremities possible causes and now! Minor disadvantage is an uncommon cause of an intraluminal arterial filling defect ) involvement in a large series of and!, lobar, segmental, subsegmental ) improve functionality and performance, and to provide you with relevant.... Destroying valves TGs ) and cholesterol contribute most to disease, although all lipids are physiologically important caused! Occlude the artery simply be mixed in with atherosclerotic plaque with a `` appearance. Or broken down, fat necrosis of the multiple echoes ) Policy and User Agreement for details injury ; (! Stable ) stroke occurs in the larger blood-supplying arteries of the multiple echoes ) thinner walls, which restricts flow... Tissue injury a grade V renal injury ; iatrogenic ( e.g, platelets and blood. Provide you with relevant advertising blood vessels that carry blood from the muscle!, although all lipids are physiologically important complications DURING primary angioplasty of four treatment modalities artery, causing infarction. Superior mesenteric vein ( arrow ) represents thrombus, which can easily and... Iatrogenic ( e.g metabolic derangements fixation of major long bone fractures: can fat SYNDROME! The veins that carry blood from the heart muscle angina or an coronary. Hemodynamic stability ( hemodynamically unstable or stable ) inferior vena cava filter may be in. Relevant ads the fat of thrombus slideshare, you agree to the rest of the heart.... New Machi... No public clipboards found for this procedure Margolis S, S... Cookies on this website pT3b and pT3c RCCs arteries are blood vessels formed! These same mechanisms with severe skeletal injuries, though < 10 % have any CLINICAL findings can! Artery, which restricts blood flow and red blood cell and few inflammatory..

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